Yale Study Identifies Cells In Placenta Susceptible To Zika

NEW HAVEN, Conn. (CBS Connecticut)  In a work published Thursday August 18, 2016, researchers at Yale have determined which kind of cells allow the Zika virus to move from an infected mother to a fetus.

Yale-New Haven Hospital resident Michael Simoni says the disease was able to multiply inside certain kinds of cells in the placenta.  “We were able to show that even if we just took a chunk of placenta, that those Hofbauer cells and fibroblasts were able to become infected, however [we’re] not entirely exactly sure how it crosses the barrier and gets into those cells in the first place.”

Yale postdoctoral fellow and co-author Kellie Ann Jurado additionally stated “These placenta-specific cells could potentially serve as a reservoir for Zika virus production within the fetal compartment.”

The work might help researchers understand which cells to focus on as they seek ways to treat the virus.



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